Which nutritional factor is specifically required for the hydroxylation of proline in the collagen matrix during bone growth?
Show answer and explanation
Correct answer: Vitamin C
Vitamin C is a necessary cofactor for the enzymes that hydroxylate proline and lysine residues in collagen. Deficiency leads to scurvy, characterized by weak bone matrix and impaired growth and healing.
Keep practicing
More Bone Growth questions
- How does the 'Zone of Ossification' (or Resorption) differ from the 'Zone of Calcification'?
- The primary ossification center establishes the:
- Which hormone is the most important stimulus for epiphyseal plate activity during childhood?
- In histology, 'Woven Bone' is typically seen in which scenario?
- Which of the following is a key histological difference between the periosteum and the endosteum during growth?
- Estrogen and testosterone affect bone growth during puberty by: