Bone Growth · Histology

What is the specific role of the 'Osteoid Seam' in bone growth?

  1. It is the unmineralized matrix awaiting calcification.
  2. It marks the area where osteoclasts are most active.
  3. It acts as a barrier to prevent blood vessel invasion.
  4. It is the site where secondary ossification begins.
Show answer and explanation

Correct answer: It is the unmineralized matrix awaiting calcification.

The osteoid seam is a thin, pale-staining layer of organic matrix (mostly Type I collagen) that has not yet undergone mineralization. It is always present on surfaces where active appositional growth is taking place.

Difficulty: Medium Question 7 of 20

Practice all 20 Bone Growth questions

Keep practicing

More Bone Growth questions