Which artifact is characterized by a blue haze or 'smudging' of the nuclear detail?
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Correct answer: Heat artifact from electrocautery
Electrocautery used during surgery 'cooks' the tissue, causing thermal denaturation of proteins. This results in dark, smudged nuclei that lack distinct chromatin patterns, often seen at the biopsy edges.
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More Histological Artifacts questions
- Folds or wrinkles in a tissue section that cannot be removed on the water bath are often due to:
- Which of the following is a common 'contaminant artifact' seen as refractile, jagged crystals?
- The 'hole' seen in the middle of a tissue section after it is placed on a slide is often caused by:
- During H&E staining, if the nuclei appear brown instead of blue, the most likely cause is:
- Which of the following artifacts is most likely caused by improper dehydration or incomplete infiltration of paraffin during tissue process…
- What is the primary cause of 'chatter' or microscopic vibrations seen in a histological section?