Folds or wrinkles in a tissue section that cannot be removed on the water bath are often due to:
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Correct answer: Poorly processed, soft tissue
If tissue is under-processed and soft, it lacks the structural integrity to flatten out on the water bath. The internal support is insufficient, causing the paraffin and tissue to compress and fold permanently.
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More Histological Artifacts questions
- Which of the following is a common 'contaminant artifact' seen as refractile, jagged crystals?
- The 'hole' seen in the middle of a tissue section after it is placed on a slide is often caused by:
- During H&E staining, if the nuclei appear brown instead of blue, the most likely cause is:
- Which of the following artifacts is most likely caused by improper dehydration or incomplete infiltration of paraffin during tissue process…
- What is the primary cause of 'chatter' or microscopic vibrations seen in a histological section?
- Which artifact appears as dark, needle-like brown crystals, often occurring when the pH of the fixative falls below 6.0?