Transcription and RNA Processing · Zoology

The 'TATA box' is a conserved promoter element in eukaryotes. What is its primary function during transcription initiation?

  1. It serves as the binding site for the sigma factor in prokaryotes
  2. It acts as a transcription termination signal for RNA polymerase
  3. It recruits TATA-binding protein to position the pre-initiation complex
  4. It is the site where the poly-A tail is added post-transcriptionally
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Correct answer: It recruits TATA-binding protein to position the pre-initiation complex

The TATA box is located approximately 25-30 base pairs upstream of the transcription start site. It is recognized by the TATA-binding protein (TBP), a subunit of TFIID, which coordinates assembly of the pre-initiation complex at the promoter.

Difficulty: Medium Question 2 of 20

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