What happens to the histones in eukaryotic cells during DNA replication?
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Correct answer: They are displaced and then reassembled on both daughter strands
As the replication fork progresses, nucleosomes are transiently disrupted. Old histones are distributed to both daughter strands, and newly synthesized histones are deposited by chaperone proteins such as CAF-1, restoring chromatin structure on each daughter duplex.
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More DNA Replication: Mechanisms and Enzymes questions
- Which enzyme is responsible for unwinding the DNA double helix at the replication fork by breaking hydrogen bonds between nitrogenous bases?
- During DNA replication, the 'Leading Strand' is synthesized in which manner?
- What is the function of Single-Strand Binding Proteins (SSBs) during the replication process?
- Which enzyme relieves the torsional strain and supercoiling created ahead of the replication fork?
- DNA Polymerase III requires a free 3'-OH group to begin synthesis. Which enzyme provides this by creating a short RNA sequence?
- The discontinuous segments of DNA synthesized on the lagging strand are known as: