Cytoskeleton and Its Filaments · Zoology

Which of the following is a key functional difference between intermediate filaments and the other two cytoskeletal components?

  1. Intermediate filaments are highly polar, like microtubules
  2. Intermediate filaments do not require ATP or GTP for assembly
  3. Intermediate filaments serve as tracks for cytoplasmic motor proteins
  4. Intermediate filaments are the thinnest cytoskeletal elements
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Correct answer: Intermediate filaments do not require ATP or GTP for assembly

Unlike microtubules (GTP-dependent) and microfilaments (ATP-dependent), intermediate filaments lack structural polarity and do not require nucleotide hydrolysis for polymerization. Their primary role is providing mechanical tensile strength to the cell, not facilitating transport or motility.

Difficulty: Medium Question 8 of 20

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