Cytoskeleton and Its Filaments · Zoology

In the context of muscle contraction, actin filaments interact with which motor protein?

  1. Dynein, a minus-end-directed motor
  2. Kinesin, a plus-end-directed motor
  3. Myosin, which binds actin and uses ATP
  4. Troponin, a regulatory actin-binding protein
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Correct answer: Myosin, which binds actin and uses ATP

Myosin is the motor protein that directly interacts with actin filaments. In muscle cells, myosin II heads bind to actin and undergo ATP-driven conformational changes that generate the sliding force responsible for sarcomere shortening. Dynein and kinesin are microtubule-based motors, while troponin regulates actin-myosin interaction but is not itself a motor protein.

Difficulty: Medium Question 7 of 20

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