Cytoskeleton and Its Filaments · Zoology

The 'treadmilling' phenomenon in actin filaments occurs when:

  1. The filament continuously rotates around its longitudinal axis
  2. Subunit loss at the minus end matches subunit gain at the plus end
  3. Motor proteins carry the whole filament across the cell membrane
  4. The filament rapidly depolymerizes when cellular ATP is depleted
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Correct answer: Subunit loss at the minus end matches subunit gain at the plus end

Treadmilling occurs when the rate of G-actin addition at the barbed (plus) end exactly equals the rate of loss at the pointed (minus) end. The filament maintains a constant length while effectively translocating, a process important for cell motility and cytoplasmic reorganization.

Difficulty: Medium Question 14 of 20

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