Cytoskeleton and Its Filaments · Zoology

What is the role of the gamma-tubulin ring complex (γ-TuRC)?

  1. It caps the plus end of microtubules to halt further growth
  2. It templates microtubule nucleation at the centrosome
  3. It severs actin filaments near the leading edge to increase fluidity
  4. It anchors intermediate filaments to the inner plasma membrane
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Correct answer: It templates microtubule nucleation at the centrosome

The gamma-tubulin ring complex (gamma-TuRC) is concentrated at the centrosome and serves as the nucleation template from which alpha/beta-tubulin dimers begin to polymerize. It defines the minus end of nascent microtubules and ensures they grow outward toward the cell periphery.

Difficulty: Medium Question 12 of 20

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