Neurophysiology and Synapses · USMLE Step 1

Which synapse type is most likely to contribute to synchronized firing of a network of neurons because of its rapid transmission and bidirectional signaling?

  1. Chemical synapse with GABA receptor
  2. Ribbon synapse
  3. Electrical synapse via gap junctions
  4. Metabotropic receptor-mediated synapse
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Correct answer: Electrical synapse via gap junctions

Electrical synapses use gap junctions to allow direct current flow between neurons, facilitating very rapid and often bidirectional signaling, which can synchronize activity across neuronal networks.

Difficulty: Medium Question 24 of 28

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