Cardiac Cycle and Hemodynamics · USMLE Step 1

Which factor does NOT increase stroke volume under physiologic conditions?

  1. Increased preload
  2. Increased contractility
  3. Decreased afterload
  4. Increased afterload
Show answer and explanation

Correct answer: Increased afterload

Stroke volume increases with increased preload or contractility and decreases with increased afterload, because higher afterload means the ventricle must work against greater resistance, reducing ejection.

Difficulty: Medium Question 4 of 21

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