Cardiac Cycle and Hemodynamics · USMLE Step 1

What effect does an acute increase in systemic vascular resistance (i.e., increased afterload) have on stroke volume if other factors remain constant?

  1. Stroke volume increases
  2. Stroke volume remains unchanged
  3. Stroke volume decreases
  4. Stroke volume becomes equal to end-diastolic volume
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Correct answer: Stroke volume decreases

An acute increase in afterload makes it harder for the ventricle to eject blood. If preload and contractility remain constant, stroke volume will decrease.

Difficulty: Medium Question 10 of 21

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