Cardiac Cycle and Hemodynamics · USMLE Step 1

During which part of the cardiac cycle does isovolumetric relaxation occur?

  1. Immediately after atrial systole ends
  2. After aortic valve closes, before mitral opens
  3. During rapid ventricular ejection of blood
  4. During atrial contraction phase
Show answer and explanation

Correct answer: After aortic valve closes, before mitral opens

Isovolumetric relaxation follows aortic valve closure and precedes opening of the mitral valve; ventricles relax, pressure falls, but volume remains constant because all valves are closed.

Difficulty: Medium Question 11 of 21

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