Cardiac Cycle and Hemodynamics · USMLE Step 1

Which event in the cardiac cycle corresponds most closely with the peak of the QRS complex on ECG in the context of mechanical events?

  1. Onset of atrial contraction
  2. Closure of semilunar valves
  3. Isovolumetric contraction
  4. Isovolumetric relaxation
Show answer and explanation

Correct answer: Isovolumetric contraction

The QRS complex represents ventricular depolarization, which triggers ventricular contraction. Mechanically, this corresponds to isovolumetric contraction phase, as ventricles generate pressure with all valves closed.

Difficulty: Medium Question 16 of 21

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