Endocrine pharmacotherapy Practice Questions
20 free Endocrine pharmacotherapy practice questions for the USMLE Step 1, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.
Questions
20 questions
All Endocrine pharmacotherapy questions
- Q1. A patient with type 2 diabetes is started on metformin. Which mechanism best explains how this drug lowers blood glucose?
- Q2. A patient on methimazole for Graves disease develops fever and sore throat. Which test should be obtained immediately?
- Q3. A woman with hypothyroidism is switched from levothyroxine to liothyronine. Which major pharmacologic difference should the physician consider?
- Q4. A diabetic patient begins therapy with a sulfonylurea. Which adverse effect is the patient most at risk for?
- Q5. A patient with type 2 diabetes is started on a GLP-1 analog such as liraglutide. Which additional benefit is expected?
- Q6. A patient with Cushing syndrome undergoes medical therapy before surgery. Which drug inhibits 11β-hydroxylase?
- Q7. A patient with osteoporosis is started on alendronate. Which adverse effect should be emphasized?
- Q8. A woman with acromegaly is prescribed octreotide. Which hormone does this drug primarily inhibit?
- Q9. A patient on an SGLT2 inhibitor such as canagliflozin should be monitored for which adverse effect?
- Q10. A patient with hyperprolactinemia is treated with bromocriptine. What is the mechanism of action?
- Q11. A patient taking long-term prednisone suddenly stops the medication. Which complication is most likely?
- Q12. A patient is prescribed propylthiouracil (PTU). Which mechanism distinguishes PTU from methimazole?
- Q13. A patient with type 1 diabetes begins insulin glargine. What is a major benefit of this formulation?
- Q14. Which diabetes medication should be avoided in patients with heart failure due to fluid retention?
- Q15. A woman with PCOS is prescribed spironolactone. What symptom is this medication intended to treat?
- Q16. A patient receiving insulin therapy experiences hypoglycemia with confusion and sweating. Which is the fastest treatment option?
- Q17. A patient with hyperthyroidism is treated with radioactive iodine. Which side effect is most likely?
- Q18. A diabetic patient is taking acarbose. What is the drug’s primary mechanism?
- Q19. A patient with adrenal insufficiency requires lifelong replacement therapy. Which medication provides mineralocorticoid activity?
- Q20. A patient on exenatide reports nausea and early satiety. What explains these symptoms?