Endocrine pharmacotherapy · USMLE Step 1

Which diabetes medication should be avoided in patients with heart failure due to fluid retention?

  1. Metformin
  2. Pioglitazone
  3. Acarbose
  4. Sitagliptin
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Correct answer: Pioglitazone

Thiazolidinediones like pioglitazone can cause edema and worsen heart failure.

Difficulty: Medium Question 14 of 20

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