Chemotherapy and Toxicology · USMLE Step 1

Which type of chemotherapy drug would be most effective during S-phase of the cell cycle?

  1. Alkylating agent
  2. Antimetabolite
  3. Vinca alkaloid
  4. Bleomycin
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Correct answer: Antimetabolite

Antimetabolites act during the S-phase when DNA synthesis occurs by interfering with nucleotide synthesis or incorporation.

Difficulty: Medium Question 12 of 20

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