Which feature is a reason for using combination chemotherapy regimens rather than monotherapy?
Show answer and explanation
Correct answer: Less resistance and multi-phase killing
Combination chemotherapy uses drugs with different mechanisms and cell-cycle specificity to reduce drug resistance, kill more cancer cells, and target multiple phases of cell division.
Keep practicing
More Chemotherapy and Toxicology questions
- Which chemotherapy agent class is derived from plant alkaloids and disrupts mitosis by stabilizing microtubules rather than preventing thei…
- Which chemotherapy agent is most likely to cause mucositis, alopecia, and bone marrow suppression shortly after administration?
- Which class of chemotherapy agents works by forming DNA crosslinks that prevent replication and transcription, acting in a cell-cycle–nonsp…
- Which toxic effect is most characteristic of platinum-based agents like cisplatin or carboplatin?
- Which chemotherapy drug class mimics normal nucleotides to block DNA synthesis during S-phase?
- Which of the following is a major dose-limiting toxicity of many chemotherapy agents affecting rapidly dividing bone marrow cells?