Chemotherapy and Toxicology · USMLE Step 1

Which of the following is a risk of long-term alkylating agent chemotherapy, even after client has recovered from initial treatment?

  1. Reversible alopecia
  2. Secondary malignancy/leukemia
  3. Transient nausea and vomiting
  4. Acute infusion reaction
Show answer and explanation

Correct answer: Secondary malignancy/leukemia

Alkylating agents are carcinogenic; they can cause DNA damage in normal cells leading to secondary malignancies or therapy-related leukemia years later.

Difficulty: Medium Question 14 of 20

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