Chemotherapy and Toxicology · USMLE Step 1

Which of the following is a major dose-limiting toxicity of many chemotherapy agents affecting rapidly dividing bone marrow cells?

  1. Cardiotoxicity
  2. Myelosuppression
  3. Peripheral neuropathy
  4. Pulmonary fibrosis
Show answer and explanation

Correct answer: Myelosuppression

Myelosuppression is common because chemo targets proliferating cells; bone marrow stem cells are highly proliferative, so they are especially vulnerable.

Difficulty: Medium Question 4 of 20

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