Cardiovascular pharmacology · USMLE Step 1

A patient with hypertension and type 2 diabetes is started on losartan. Which additional benefit besides BP reduction does losartan provide?

  1. Causes hyperkalemia without added benefit
  2. Slows progression of diabetic nephropathy
  3. Markedly increased insulin resistance
  4. Reliable dry cough prevention
Show answer and explanation

Correct answer: Slows progression of diabetic nephropathy

ARBs like losartan reduce glomerular hypertension and proteinuria, thereby slowing the progression of diabetic nephropathy in patients with diabetes and hypertension.

Difficulty: Medium Question 13 of 20

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