Which factor influences whether tissue injury heals by regeneration or progresses to fibrosis and permanent organ damage?
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Correct answer: Injury severity and duration, tissue regenerative capacity, and chronic inflammation
Regeneration vs fibrosis depends on the severity and chronicity of injury, the inherent regenerative ability of the tissue (e.g., liver vs myocardium), and whether inflammation resolves; chronic or repeated injury favors fibrosis.
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