In left ventricular hypertrophy due to chronic hypertension, which structural change impairs diastolic filling and contributes to heart failure?
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Correct answer: Interstitial fibrosis reducing myocardial compliance
Hypertension causes myocyte hypertrophy and interstitial fibrosis; the fibrotic deposition reduces myocardial compliance and impairs diastolic filling, contributing to heart failure.
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