Viruses: Life Cycle and Disease · USMLE Step 1

A patient develops muscle paralysis due to poliovirus. Which receptor does poliovirus use for entry?

  1. CD155 (PVR)
  2. CD55 (DAF)
  3. CD4
  4. CCR5
Show answer and explanation

Correct answer: CD155 (PVR)

Poliovirus binds CD155 (also called PVR or Necl-5) on host cells. It is a picornavirus that spreads through the GI tract.

Difficulty: Medium Question 5 of 20

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