Hypersensitivity and Autoimmunity · USMLE Step 1

A patient with systemic lupus erythematosus develops glomerulonephritis due to circulating immune complexes. This reflects which hypersensitivity type?

  1. Type I
  2. Type II
  3. Type III
  4. Type IV
Show answer and explanation

Correct answer: Type III

Type III hypersensitivity results from deposition of antigen-antibody complexes in tissues. This triggers complement activation and inflammation.

Difficulty: Medium Question 3 of 20

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