Hypersensitivity and Autoimmunity · USMLE Step 1

A patient undergoes a PPD skin test. After 48 hours, a firm erythematous induration appears. Which hypersensitivity type is this?

  1. Type I
  2. Type II
  3. Type III
  4. Type IV
Show answer and explanation

Correct answer: Type IV

Type IV hypersensitivity is T-cell–mediated and delayed. The PPD test measures a memory T-cell response to tuberculosis antigens.

Difficulty: Medium Question 4 of 20

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