Stem Cells and Regeneration · USMLE Step 1

Which of the following processes describes tissue regeneration by proliferation and differentiation of stem or progenitor cells after injury?

  1. Fibrosis with scar formation
  2. Stem cell–mediated regeneration
  3. Apoptosis of damaged cells only
  4. Transient inflammation without proliferation
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Correct answer: Stem cell–mediated regeneration

Stem cell–mediated regeneration involves activation of stem or progenitor cells, which proliferate and differentiate to replace lost or damaged cells, restoring tissue structure and function.

Difficulty: Medium Question 10 of 20

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