Stem Cells and Regeneration · USMLE Step 1

Which of the following best describes a risk associated with uncontrolled use of pluripotent stem cells in regenerative therapy?

  1. They may differentiate into unrelated cell lineages far too quickly
  2. They may permanently lose their ability to divide
  3. They may form tumors like teratomas from uncontrolled proliferation
  4. They can only ever produce blood cells
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Correct answer: They may form tumors like teratomas from uncontrolled proliferation

Because pluripotent stem cells can differentiate into many cell types and proliferate extensively, if not properly regulated they may form teratomas or other tumors — a recognized risk in regenerative medicine.

Difficulty: Medium Question 13 of 20

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