Gene Regulation and Epigenetics · USMLE Step 1

Which statement correctly describes non-coding RNAs (ncRNAs) in epigenetic regulation?

  1. ncRNAs always code for transcription factors that drive transcription
  2. ncRNAs recruit chromatin-modifying complexes to specific loci
  3. ncRNAs permanently alter the underlying genomic DNA sequence
  4. ncRNAs are expressed only in embryonic stem cells during development
Show answer and explanation

Correct answer: ncRNAs recruit chromatin-modifying complexes to specific loci

Non-coding RNAs (like lncRNAs or miRNAs) can guide chromatin-modifying complexes to particular genomic regions, influencing chromatin state and gene expression without altering DNA sequence.

Difficulty: Medium Question 20 of 20

Practice all 20 Gene Regulation and Epigenetics questions

Keep practicing

More Gene Regulation and Epigenetics questions