Which of the following proteins stabilize single-stranded DNA during replication to prevent re-annealing or degradation?
Show answer and explanation
Correct answer: Single-strand binding proteins (SSBs)
Single-strand binding proteins (SSBs) bind to unwound single-stranded DNA at the replication fork, preventing the strands from re-forming a duplex or forming secondary structures.
Keep practicing
More DNA Structure and Replication questions
- What is the role of topoisomerase (or DNA gyrase in prokaryotes) during DNA replication?
- Which DNA polymerase performs the bulk of leading-strand synthesis in prokaryotes during replication?
- Which of the following correctly describes the directionality of new DNA strand synthesis by DNA polymerase?
- Why are Okazaki fragments necessary on the lagging strand during DNA replication?
- Which component forms the “replisome” complex at the replication fork in prokaryotes?
- Which statement correctly describes the number of origins of replication in prokaryotic versus eukaryotic chromosomes?