Which component forms the “replisome” complex at the replication fork in prokaryotes?
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Correct answer: Helicase + primase + DNA Pol III holoenzyme
The replisome in prokaryotes comprises helicase, primase, and the DNA Pol III holoenzyme working together at each replication fork to coordinate unwinding, primer synthesis, and DNA elongation.
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More DNA Structure and Replication questions
- Which statement correctly describes the number of origins of replication in prokaryotic versus eukaryotic chromosomes?
- Which of the following polymerases is primarily responsible for lagging-strand elongation in eukaryotic cells?
- What problem at the ends of linear eukaryotic chromosomes is addressed by the enzyme telomerase during replication?
- What is the role of single-stranded DNA binding proteins (SSBs) during replication?
- During DNA replication, which enzyme replaces RNA primers on the lagging strand with DNA in prokaryotes?
- Which of the following is NOT required for formation of the replication fork during DNA replication?