Liver and Pancreas Functions · Physiology

A patient with severe liver failure often exhibits bruising and prolonged bleeding. This is primarily due to the liver's inability to synthesize which of the following?

  1. Vitamin K from the diet
  2. Clotting factors like prothrombin
  3. Platelets in the bone marrow
  4. Tissue plasminogen activator (tPA)
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Correct answer: Clotting factors like prothrombin

The liver synthesizes nearly all essential coagulation factors, including factors I (fibrinogen), II (prothrombin), VII, IX, and X. Deficiency in these proteins leads to impaired clot formation and increased bleeding risk.

Difficulty: Medium Question 23 of 40

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