Absorption mechanisms · Physiology

Which of the following transporters is responsible for the uptake of glucose and galactose across the apical membrane of the enterocyte against their concentration gradient?

  1. GLUT2
  2. GLUT5
  3. SGLT1
  4. SGLT2
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Correct answer: SGLT1

SGLT1 (Sodium-Glucose Linked Transporter 1) utilizes the sodium gradient created by the Na+/K+ ATPase to co-transport glucose or galactose into the cell. This is a primary example of secondary active transport in the small intestine.

Difficulty: Medium Question 21 of 40

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