Bronchodilators · Pharmacology

What is the role of Roflumilast in respiratory pharmacology?

  1. It is a SABA used for rescue therapy
  2. It is a selective PDE4 inhibitor used to reduce COPD exacerbations
  3. It is a LAMA used for night-time asthma
  4. It is a monoclonal antibody against IgE
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Correct answer: It is a selective PDE4 inhibitor used to reduce COPD exacerbations

Roflumilast is an oral, selective phosphodiesterase-4 (PDE4) inhibitor. It is not a direct bronchodilator but is used to reduce the risk of exacerbations in patients with severe COPD associated with chronic bronchitis.

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