Bronchodilators · Pharmacology

Aclidinium bromide is a bronchodilator characterized by:

  1. Twice-daily LAMA dosing
  2. Rapid metabolism in the plasma by esterases
  3. Use as a rescue inhaler
  4. Selective inhibition of the M2 receptor
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Correct answer: Rapid metabolism in the plasma by esterases

Aclidinium is a LAMA that is rapidly hydrolyzed by plasma esterases. This rapid metabolism helps limit the systemic anticholinergic side effects compared to other long-acting agents.

Difficulty: Medium Question 17 of 20

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