Non-steroidal anti-inflammatory drugs (NSAIDs) can reduce the diuretic effect of Furosemide by inhibiting the synthesis of:
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Correct answer: Prostaglandins
Prostaglandins, specifically PGE2, maintain renal blood flow and antagonize the effects of ADH. Loop diuretics stimulate PGE2 production; therefore, NSAIDs block this effect, leading to reduced renal perfusion and attenuated diuresis.
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More Loop Diuretics questions
- What is the primary site of action for loop diuretics within the nephron?
- Which of the following is a potential endocrine side effect of chronic loop diuretic therapy?
- Loop diuretics increase the excretion of which of the following into the urine?
- In the treatment of severe hypercalcemia, loop diuretics are administered along with which of the following to prevent volume depletion?
- Which electrolyte disturbance caused by loop diuretics can increase the risk of Digoxin toxicity?
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