Loop Diuretics · Pharmacology

Which of the following is a potential endocrine side effect of chronic loop diuretic therapy?

  1. Hypoglycemia
  2. Hyperglycemia
  3. Hypothyroidism
  4. Adrenal insufficiency
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Correct answer: Hyperglycemia

Loop diuretics can cause impaired glucose tolerance and hyperglycemia. This is largely attributed to hypokalemia, which reduces the release of insulin from pancreatic beta cells.

Difficulty: Medium Question 14 of 20

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