Loop Diuretics · Pharmacology

In the treatment of severe hypercalcemia, loop diuretics are administered along with which of the following to prevent volume depletion?

  1. 5% Dextrose
  2. Normal Saline
  3. Thiazide diuretics
  4. Potassium chloride
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Correct answer: Normal Saline

Loop diuretics promote calcium excretion (calciuria). To safely treat hypercalcemia, large volumes of normal saline must be infused simultaneously to maintain GFR and prevent the dehydration that would otherwise limit the diuretic effect.

Difficulty: Medium Question 16 of 20

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