Which monoclonal antibody targets the CD20 antigen on B-lymphocytes and is used to treat Non-Hodgkin Lymphoma?
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Correct answer: Rituximab
Rituximab binds to the CD20 antigen found on the surface of normal and malignant B-cells. This binding triggers cell death through complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC).
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