What is the primary mechanism of action of Omalizumab in the management of severe asthma?
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Correct answer: It binds free IgE, preventing it from attaching to mast cells
Omalizumab is a humanized monoclonal antibody that selectively binds to circulating IgE. This prevents IgE from attaching to the high-affinity FcεRI receptors on mast cells and basophils, thereby limiting the allergic inflammatory response.
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