What is the primary goal of drug metabolism (biotransformation) in the body?
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Correct answer: To convert the drug into a more polar, water-soluble form for excretion
Most drugs are lipid-soluble and would be reabsorbed by the renal tubules if not metabolized. Biotransformation adds or exposes polar groups, making the metabolites water-soluble so they can be easily eliminated by the kidneys.
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More Drug Metabolism questions
- Which of the following reactions is categorized as a Phase I metabolic reaction?
- The Cytochrome P450 (CYP) enzyme system is primarily located in which organelle of the hepatocyte?
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