Drug Metabolism · Pharmacology

What is a 'Prodrug' in pharmacology?

  1. A drug that damages liver cells even at normal therapeutic doses
  2. An inactive compound that the body converts into an active metabolite
  3. An active drug that is excreted unchanged by the kidneys without metabolism
  4. A drug that bypasses the liver entirely after oral administration
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Correct answer: An inactive compound that the body converts into an active metabolite

Prodrugs, such as Enalapril or Codeine, are designed to be inactive when administered. Metabolic processes, often in the liver, are required to transform them into their active forms to exert a therapeutic effect.

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