The 'P-glycoprotein' (P-gp) transporter in the enterocytes of the GI tract primarily functions to:
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Correct answer: Pump drugs out of the cell back into the intestinal lumen
P-glycoprotein is an efflux transporter that acts as a biological barrier. By pumping absorbed drug molecules back into the gut lumen, it decreases the overall bioavailability of many pharmacological agents.
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