The term 'Bioequivalence' between two drug products means they have:
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Correct answer: The same rate and extent of absorption (AUC and $C_{max}$)
Two products are bioequivalent if their bioavailability profiles (Area Under the Curve and maximum concentration) are within a predefined statistical range. This is the standard used to approve generic versions of brand-name drugs.
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More Drug Absorption questions
- Absorption via the sublingual route is advantageous for drugs like Nitroglycerin because:
- Which of the following describes the 'pH Partition Hypothesis'?
- What effect does 'ion trapping' have on a basic drug in the stomach (pH 1.5)?
- Which property is most desirable for a drug to be absorbed via passive diffusion across the lipid bilayer of a cell membrane?
- The Area Under the Curve (AUC) in a plasma concentration-time graph represents:
- Which route of administration provides 100% bioavailability by definition?