Which of the following H2 blockers is well known for inhibiting multiple Cytochrome P450 (CYP) enzymes, leading to many drug interactions?
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Correct answer: Cimetidine
Cimetidine is a potent inhibitor of several CYP450 isoforms, including 1A2, 2C9, and 2D6. This can significantly increase the serum levels of drugs like warfarin, phenytoin, and theophylline.
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