Compared to Proton Pump Inhibitors (PPIs), H2 blockers are generally considered:
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Correct answer: Less potent but faster-acting for episodic heartburn
H2RAs have a more rapid onset of action than PPIs, making them useful for the 'as-needed' treatment of mild, episodic dyspepsia. However, they are less effective at overall 24-hour acid suppression.
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More H2 Blockers questions
- A patient develops 'tachyphylaxis' within 2–6 days of starting an H2 blocker. What does this term imply in this context?
- Which H2-receptor antagonist has the highest potency and the longest duration of action among the following?
- H2 blockers are particularly effective at inhibiting which type of gastric acid secretion?
- Which of the following H2RAs is primarily eliminated by the kidneys and has nearly 100% oral bioavailability?
- In elderly patients, high doses of Cimetidine can occasionally cause which central nervous system side effect?
- Why is dose adjustment necessary for H2 blockers in patients with chronic kidney disease?