Which of the following side effects of opioids does NOT typically diminish over time due to the development of tolerance?
Show answer and explanation
Correct answer: Constipation
While tolerance develops rapidly to the analgesic, sedative, and emetic effects of opioids, it develops very slowly or not at all to miosis and constipation. Patients on chronic opioid therapy almost always require a bowel regimen.
Keep practicing
More Opioids questions
- Methadone is used in detoxification programs primarily because it:
- Which opioid can cause pupillary dilation rather than miosis in overdose, and may trigger serotonin syndrome when combined with SSRIs?
- Loperamide is used as an antidiarrheal medication because it:
- Which opioid analgesic also acts as an inhibitor of both norepinephrine and serotonin reuptake?
- What is the mechanism of the 'itching' or pruritus often felt by patients after an injection of Morphine?
- Why is Codeine often considered a 'prodrug'?