Opioid-induced 'chest wall rigidity' is a potential complication most commonly associated with the rapid IV administration of which drug?
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Correct answer: Fentanyl
Rapid IV infusion of highly potent lipophilic opioids like fentanyl can cause sudden rigidity of the truncal muscles, making ventilation difficult. This effect is thought to be mediated through central dopaminergic and GABAergic pathways.
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