Which organ is primarily responsible for the metabolism of amide local anesthetics?
Show answer and explanation
Correct answer: Liver
Amide local anesthetics are metabolized mainly in the liver by hepatic enzymes. This contrasts with ester anesthetics, which are metabolized by plasma esterases.
Keep practicing
More Local Anesthetics questions
- Which local anesthetic is commonly used as a topical anesthetic in sprays and gels?
- Which property of a local anesthetic influences its ability to penetrate nerve membranes?
- Which factor mainly determines the duration of action of a local anesthetic?
- Which clinical use is common for local anesthetics?
- Which condition may reduce the effectiveness of local anesthetics?
- Which stage of nerve impulse transmission is blocked by local anesthetics?